abstract：OBJECTIVE:To compare the sensitivity to atrial natriuretic peptide (ANP) in young and elderly subjects. DESIGN:Double-blind, random-order, placebo-controlled study using two different rates of ANP infusion. SUBJECTS:Eight healthy young (23 +/- 3 years, mean +/- SD) and eight healthy elderly (76 +/- 4 years) subjects ...

journal_title：Journal of the American Geriatrics Society

authors： Tan AC,Jansen TL,Thien T,Kloppenborg PW,Benraad TJ

更新日期：1993-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the skeletal health, calcium, and vitamin D homeostasis of patients upon their entry to a long-term-care facility. Factors that could contribute to the risk of future osteoporotic fractures were also evaluated. DESIGN:Cross-sectional study. PATIENTS:Two hundred eighty-seven consecutive admission...

journal_title：Journal of the American Geriatrics Society

authors： Komar L,Nieves J,Cosman F,Rubin A,Shen V,Lindsay R

更新日期：1993-10-01 00:00:00

abstract：:The contribution of frailty to human morbidity and mortality is immense. Yet it lacks a conceptual framework. By borrowing from the hypotheses provided by the thermophysicists, frailty can be understood in a way that both interrelates the relationship between form and function and provides medical science with an oper...

journal_title：Journal of the American Geriatrics Society

authors： Bortz WM 2nd

更新日期：1993-09-01 00:00:00

abstract：OBJECTIVE:Validation of a new instrument for screening dementia, the Cross Cultural Cognitive Examination (CCCE), is described. DESIGN:Criterion and concurrent validation and cross-cultural comparison of a new instrument. PARTICIPANTS:All individuals over the age of 40 in a village in southern Guam participated in a ...

journal_title：Journal of the American Geriatrics Society

authors： Glosser G,Wolfe N,Albert ML,Lavine L,Steele JC,Calne DB,Schoenberg BS

更新日期：1993-09-01 00:00:00

abstract：OBJECTIVE:To determine whether serum thyrotropin (TSH) levels are altered in euthyroid older persons compared with middle-aged adults. DESIGN:Serum TSH and thyroid hormone levels were measured in a large group of older persons (> 70 years old, n = 216) and their middle-aged offspring (40-60 years old, n = 211) after e...

journal_title：Journal of the American Geriatrics Society

authors： Hershman JM,Pekary AE,Berg L,Solomon DH,Sawin CT

更新日期：1993-08-01 00:00:00

abstract：OBJECTIVE:To assess the validity of several equations for estimating creatinine clearance in a large sample of high-functioning, community-dwelling elderly. DESIGN:Serum and 12-hour urine samples were collected and assayed for creatinine using the Jaffe total chromagen method. Fifteen clearance-estimating equations we...

journal_title：Journal of the American Geriatrics Society

authors： Malmrose LC,Gray SL,Pieper CF,Blazer DG,Rowe JW,Seeman TE,Albert MS

更新日期：1993-07-01 00:00:00

abstract：:As nursing homes become increasingly important sites for biomedical and behavioral research, researchers must address the ethical problems of increased vulnerability and the high prevalence of mental and physical disorders in the nursing home population. Obtaining valid informed consent is but one of the many difficul...

journal_title：Journal of the American Geriatrics Society

authors： Sachs GA,Rhymes J,Cassel CK

更新日期：1993-07-01 00:00:00

abstract：OBJECTIVE:This study intends to determine what role fiberoptic bronchoscopy (FOB) plays in the diagnosis of tuberculosis (TB), particularly in a geriatric population. DESIGN:Cases of tuberculosis reported to the Tennessee Department of Health during the years 1989 and 1990 were divided into two age groups: Group A (< ...

journal_title：Journal of the American Geriatrics Society

authors： Patel YR,Mehta JB,Harvill L,Gateley K

更新日期：1993-06-01 00:00:00

abstract：OBJECTIVE:To determine medical, ophthalmologic, and demographic predictors of cognitive function scores as measured by the Telephone Interview for Cognitive Status (TICS), an adaptation of the Folstein Mini-Mental Status Exam. A secondary objective was to perform an item-by-item analysis of the TICS scores to determine...

journal_title：Journal of the American Geriatrics Society

authors： Mangione CM,Seddon JM,Cook EF,Krug JH Jr,Sahagian CR,Campion EW,Glynn RJ

更新日期：1993-05-01 00:00:00

abstract：OBJECTIVE:To investigate the prevalence of hypoalbuminemia and hypoprealbuminemia in hospitalized, elderly, skilled nursing facility residents and to correlate these findings with clinical outcomes. DESIGN:Prospective cohort study. SETTING:A 300-bed community hospital. PARTICIPANTS:Eighty-one hospitalized, skilled n...

journal_title：Journal of the American Geriatrics Society

authors： Ferguson RP,O'Connor P,Crabtree B,Batchelor A,Mitchell J,Coppola D

更新日期：1993-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the use of pentoxifylline to treat impotence in men with mild to moderate penile vascular insufficiency. DESIGN:Double-blind randomized clinical trial. SETTING:Sexual Dysfunction Clinic at VA Medical Center, Sepulveda, CA. PARTICIPANTS:Convenience sample of couples. INTERVENTION:Twelve weeks o...

journal_title：Journal of the American Geriatrics Society

authors： Korenman SG,Viosca SP

更新日期：1993-04-01 00:00:00

abstract：OBJECTIVE:To determine the influences of age and risk group on the survival of AIDS patients. We concentrated on transfusion because it is the commonest risk factor for AIDS in patients over 70 years of age. DESIGN:Survival curve regression analysis. PARTICIPANTS:Patients aged 13 years and over with AIDS acquired thr...

journal_title：Journal of the American Geriatrics Society

authors： Sutin DG,Rose DN,Mulvihill M,Taylor B

更新日期：1993-03-01 00:00:00

abstract：:Research indicates that lower extremity muscle weakness in the elderly is consistently related to impaired mobility and fall risk. Reversible components of the muscle weakness of aging include underuse syndromes and undernutrition, both of which are prevalent in nursing home populations. The Boston FICSIT study is a n...

journal_title：Journal of the American Geriatrics Society

authors： Fiatarone MA,O'Neill EF,Doyle N,Clements KM,Roberts SB,Kehayias JJ,Lipsitz LA,Evans WJ

更新日期：1993-03-01 00:00:00

abstract：OBJECTIVE:To examine public opinion regarding certain elements of consent: disclosure, advance directives, substitute decisions, emergency treatment, and advocacy. DESIGN:Cross-sectional random-digit-dialing telephonic survey. SETTING:General public. PARTICIPANTS:One thousand randomly-selected adults living in Ontar...

journal_title：Journal of the American Geriatrics Society

authors： Singer PA,Choudhry S,Armstrong J

更新日期：1993-02-01 00:00:00

abstract：:Our objective was to determine the outcome of onsite CPR in elderly patients receiving institutional care who had access to 24-hour on-site full ACLS capability. We used a retrospective chart and CPR protocol review of all patients who received CPR during the study period; these were patients or residents in a multi-l...

journal_title：Journal of the American Geriatrics Society

authors： Gordon M,Cheung M

更新日期：1993-02-01 00:00:00

abstract：OBJECTIVE:To further validate an objective measure of physical illness burden, the Cumulative Illness Rating Scale (CIRS). DESIGN:Survey with correlation of CIRS ratings made from physician interviews and review of medical records with post-mortem ratings made independently at tissue autopsy. SUBJECTS:Victims of comp...

journal_title：Journal of the American Geriatrics Society

authors： Conwell Y,Forbes NT,Cox C,Caine ED

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:To determine predictors of 2-year post-hospitalization mortality in a cohort of elderly hospitalized patients originally assembled to assess the impact of a Geriatric Consultation Team (GCT). DESIGN:Two-year follow-up of an inception cohort. SETTING:University-affiliated tertiary care VA Medical Center. PA...

journal_title：Journal of the American Geriatrics Society

authors： Cohen HJ,Saltz CC,Samsa G,McVey L,Davis D,Feussner JR

更新日期：1992-12-01 00:00:00

abstract：OBJECTIVES:To study how well the scoring on each item of the MMSE relates to the sum-score when the purpose is to identify persons with cognitive impairment, and to identify an equally effective subset of MMSE items for predicting cognitive impairment. DESIGN:Retrospective survey of MMSE data for 850 elderly. SETTING...

journal_title：Journal of the American Geriatrics Society

authors： Braekhus A,Laake K,Engedal K

更新日期：1992-11-01 00:00:00

abstract：:There are over 2.5 million black Americans aged 65 and over living in the United States today, including some 258,000 persons aged 85 years and over. The post-World War II baby boom within the US black population should ensure that the numbers of persons aged 65 and over will increase into the 21st Century. If present...

journal_title：Journal of the American Geriatrics Society

authors： Miles TP,Bernard MA

更新日期：1992-10-01 00:00:00

abstract：OBJECTIVE:To describe the long-term outcome and complications of spinal surgery in a population of elderly patients. DESIGN:Retrospective chart review and clinical follow-up. SETTING:A 700-bed tertiary care midwestern hospital. PATIENTS:Patients 70 years of age or older who underwent elective surgical procedures for...

journal_title：Journal of the American Geriatrics Society

authors： Smith EB,Hanigan WC

更新日期：1992-09-01 00:00:00

abstract：OBJECTIVE:To study the association of two well known risk factors for breast cancer and the association of knowledge of those risk factors with mammography utilization. DESIGN:Cross sectional: two independent random telephone surveys. SETTING:Two Northeastern metropolitan communities surveyed in 1987 and in 1989. PA...

journal_title：Journal of the American Geriatrics Society

authors： Costanza ME,Stoddard A,Gaw VP,Zapka JG

更新日期：1992-08-01 00:00:00

abstract：:(-)Deprenyl (Selegiline, Jumex, Eldepryl, Movergan), a close structural relative to phenylethylamine (PEA), is a drug with a unique pharmacological spectrum. (1) It is a highly potent and selective, irreversible inhibitor of B-type monoamine oxidase (MAO), a predominantly glial enzyme in the brain. The activity of thi...

journal_title：Journal of the American Geriatrics Society

authors： Knoll J

更新日期：1992-08-01 00:00:00

abstract：OBJECTIVE:To examine changes in functional status over time by age, gender, and ethnicity in a representative sample of older persons. DESIGN:Six-year prospective cohort study. SETTING:Alameda County, California. PARTICIPANTS:508 persons 65 years old and older at baseline in 1984. MAIN OUTCOME MEASURES:Activities o...

journal_title：Journal of the American Geriatrics Society

authors： Strawbridge WJ,Kaplan GA,Camacho T,Cohen RD

更新日期：1992-08-01 00:00:00

abstract：OBJECTIVE:To determine if alcohol use is a risk factor for fall injury events among community-dwelling older persons. DESIGN:Case-control study. SETTING:South Miami Beach, Florida. PARTICIPANTS:320 persons 65 or older who sought treatment at six area hospitals for injuries resulting from falls; 609 controls, matched...

journal_title：Journal of the American Geriatrics Society

authors： Nelson DE,Sattin RW,Langlois JA,DeVito CA,Stevens JA

更新日期：1992-07-01 00:00:00

abstract：OBJECTIVE:To assess the validity of the Neurobehavioral Rating Scale (NRS) in patients with Alzheimer's disease (AD) or multi-infarct dementia (MID) and to characterize the cognitive, psychiatric, and behavioral disturbances that occur in these patients. DESIGN:Cross-sectional evaluation. SETTING:West Los Angeles VAM...

journal_title：Journal of the American Geriatrics Society

authors： Sultzer DL,Levin HS,Mahler ME,High WM,Cummings JL

更新日期：1992-06-01 00:00:00

abstract：OBJECTIVE:To compare clinical status of elderly institutionalized subjects with asymptomatic bacteriuria and normal urinary antibody to those with elevated urinary antibody to the major outer membrane of Escherichia coli. DESIGN:Retrospective review. SETTING:Long term facility for the elderly. PARTICIPANTS:Convenien...

journal_title：Journal of the American Geriatrics Society

authors： Nicolle LE,Brunka J,McIntyre M,Murray D,Harding GK

更新日期：1992-06-01 00:00:00

abstract：OBJECTIVE:To investigate the accuracy of cranial computerized tomography (CT) scans in distinguishing patients with Alzheimer's disease from those with other dementing conditions. DESIGN:Retrospective clinicopathological correlation with pre-mortem CT scans. SETTING:Urban and rural hospitals and nursing homes in the ...

journal_title：Journal of the American Geriatrics Society

authors： Mendez MF,Mastri AR,Zander BA,Frey WH 2nd

更新日期：1992-05-01 00:00:00

abstract：OBJECTIVE:To determine whether airline pilots over the age of 60 pose a hazard to aviation safety and whether risk assessment could replace age-based retirement. DATA SOURCES:A computer-assisted literature search (MEDLINE), expert consultation, and government reports. STUDY SELECTION:Original studies on flight perfor...

journal_title：Journal of the American Geriatrics Society

authors： Stuck AE,van Gorp WG,Josephson KR,Morgenstern H,Beck JC

更新日期：1992-05-01 00:00:00

abstract：OBJECTIVE:To determine patient factors that predict use of physical or occupational therapy (PT/OT) services by elderly people. DESIGN:Time-series study of the relationship of PT/OT use to a variety of characteristics present at baseline. PARTICIPANTS:Eight-hundred nine community-dwelling men and women aged 65 and ol...

journal_title：Journal of the American Geriatrics Society

authors： Mayer-Oakes SA,Hoenig H,Atchison KA,Lubben JE,De Jong F,Schweitzer SO

更新日期：1992-04-01 00:00:00

abstract：OBJECTIVE:(1) To establish the range of cerebral atrophy across the adult age spectrum in optimally healthy, rigorously evaluated individuals. (2) To determine, across the age spectrum, the relation of gender and cerebral atrophy (as measured by ventricular enlargement) to cognitive function. DESIGN:Cross-sectional co...

journal_title：Journal of the American Geriatrics Society

authors： Kaye JA,DeCarli C,Luxenberg JS,Rapoport SI

更新日期：1992-03-01 00:00:00

abstract：OBJECTIVE:To assess how dietary change affects gain in strength and muscle mass during heavy resistance training of elderly men. DESIGN:Randomized controlled trial. INTERVENTION:During 12 weeks of resistance training of knee extensors and flexors, a daily supplement of 560 +/- 16 kcal/day (17% energy from protein, 43...

journal_title：Journal of the American Geriatrics Society

authors： Meredith CN,Frontera WR,O'Reilly KP,Evans WJ

更新日期：1992-02-01 00:00:00

abstract：PURPOSE:To evaluate the use of a vacuum tumescence device in the treatment of impotence in couples wishing to restore coital function, whose male partners had unsatisfactory results from penile implants or in whom the man was impotent following treatment for prostate or colon carcinoma. SUBJECTS:Convenience sample of ...

journal_title：Journal of the American Geriatrics Society

authors： Korenman SG,Viosca SP

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:To examine physician use of stool guaiac testing in order to determine indications for testing, how the test was used, and the consequences of a particular test result. DESIGN:Retrospective case series. SETTING:Large midwestern inpatient nursing home facility. PATIENTS:All patients with positive fecal occu...

journal_title：Journal of the American Geriatrics Society

authors： Klos SE,Drinka P,Goodwin JS

更新日期：1991-12-01 00:00:00

abstract：OBJECTIVE:To assess the experience of Minnesota nursing homes with methicillin-resistant Staphylococcus aureus (MRSA) and the policies and procedures used for its control. DESIGN:A 12-question survey, with primarily categorical responses, was mailed to the Directors of Nursing of all Minnesota long-term-care facilitie...

journal_title：Journal of the American Geriatrics Society

authors： Thurn JR,Belongia EA,Crossley K

更新日期：1991-11-01 00:00:00

abstract：OBJECTIVE:We examined predictors of hospital and 6-month mortality in older Medical Intensive Care Unit (MICU) patients with particular attention to age and functional status. Age is generally thought to be strongly associated with intensive care outcomes, but this relationship may be confounded by age-related changes....

journal_title：Journal of the American Geriatrics Society

authors： Mayer-Oakes SA,Oye RK,Leake B

更新日期：1991-09-01 00:00:00

abstract：:In this paper, we present the consensus statement from a national conference on research priorities and methodologies for studying geriatric evaluation and management (GEM) programs. These conclusions, discussion points, and recommendations resulted from discussions of plenary papers, working group deliberations, and ...

journal_title：Journal of the American Geriatrics Society

authors： Kramer A,Deyo R,Applegate W,Meehan S

更新日期：1991-09-01 00:00:00

abstract：:Newly enacted Federal regulations have focused increasing attention on the use of psychoactive drugs and on the treatment of disruptive behavior in the nursing home. To study the interaction between resident behavior and staff distress in nursing homes, we measured the frequency of seven types of behavior problems amo...

journal_title：Journal of the American Geriatrics Society

authors： Everitt DE,Fields DR,Soumerai SS,Avorn J

更新日期：1991-08-01 00:00:00

abstract：:The aim of this study was to evaluate the effect of a geriatric-anesthesiologic intervention program for the prevention and treatment of acute confusional states (ACS) in elderly patients treated for femoral neck fractures. The intervention program was based on the results of previous prospective studies in similar pa...

journal_title：Journal of the American Geriatrics Society

authors： Gustafson Y,Brännström B,Berggren D,Ragnarsson JI,Sigaard J,Bucht G,Reiz S,Norberg A,Winblad B

更新日期：1991-07-01 00:00:00

abstract：:While skin tears are a common occurrence in the institutionalized elderly population, nothing has been written about this problem. We retrospectively studied all incident reports during a 1-year period at a large, urban, long-term-care facility to identify residents with skin tears. The overall incidence of skin tears...

journal_title：Journal of the American Geriatrics Society

authors： Malone ML,Rozario N,Gavinski M,Goodwin J

更新日期：1991-06-01 00:00:00

abstract：:The benefits of prophylactic aspirin therapy to prevent cardiovascular and cerebrovascular disease in asymptomatic individuals remains unclear. The rationale for developing a multicentered, double-blind, placebo-controlled clinical trial to determine whether low-dose aspirin (100 mg daily) prevents cardiovascular and ...

journal_title：Journal of the American Geriatrics Society

authors： Silagy CA,McNeil JJ,Bulpitt CJ,Donnan GA,Tonkin AM,Worsam B

更新日期：1991-05-01 00:00:00